In 1928, Scottish scientist Alexander Fleming found that a mysterious antibacterial fungus had grown on a petri dish he’d forgotten to cover in his laboratory: he discovered penicillin by accident. Scientists have sought to harness the power of chance ever since. Modern drug discovery aims to amplify Fleming’s serendipitous circumstances a millionfold: pharmaceutical companies search through combinations of molecular compounds at random, hoping to find a hit.
- Peter Thiel
Notable Quotables
Ultimately, we wanted Nike to be the world’s best sports and fitness company. Once you say that, you have a focus. You don’t end up making wing tips or sponsoring the next Rolling Stones world tour.
- Phil Knight
I was leading a lot of idea and the vision for where the product was going. Ev [Evan Williams] was funding and supporting what we were doing. He put the shelter over our heads. And Biz [Stone] was just an amazingly creative guy.
- Jack Dorsey
Duty makes us do things well, but love makes us do them beautifully.
- Zig Ziglar
I believe in God, family, and McDonald’s. And in the office, that order is reversed.
- Ray Kroc
Zero to One is about how to build companies that create new things. It draws on everything I’ve learned directly as a co-founder of PayPal and Palantir and then an investor in hundreds of startups, including Facebook and SpaceX.
- Peter Thiel
You can expect what you accept.
- Anonymous
When you do the things you need to do when you need to do them, the day will come when you can do the things you want to do when you want to do them.
- Zig Ziglar
I like a woman with a head on her shoulders. I hate necks.
- Steve Martin
If you have integrity, nothing else matters. If you don’t have integrity, nothing else matters.
- Harvey Mackay
I can’t afford this land either, but my business can.
- Robert Kiyosaki
If your only goal is to become rich, you will never achieve it.
- John D. Rockefeller
Tell your child, your spouse, or your employee that he or she is stupid or dumb at a certain thing, has no gift for it, and is doing it all wrong, and you have destroyed almost every incentive to try to improve.
- Dale Carnegie
All that hullabaloo about somebody’s net worth is just stupid, and it’s made my life a lot more complex and difficult.
- Sam Walton
A person convinced against their will Is of the same opinion still.
- Dale Carnegie
Ironically, it is exactly because we are a city that embraces freedom, that welcomes everyone and encourages their dreams, that New York remains on the front lines in the war on terror.
- Michael Bloomberg
In view of the good progress made in respect of negotiations relating to Mainland China’s entry to the World Trade Organisation and the boost in local economic activities deriving from the emergence of the new economy, a great number of technology-related and international institutions have established and expanded their businesses in Hong Kong, bringing about substantial increases both in rentals as well as capital values for prime office properties and luxury residential properties.
- Lee Shau Kee
By providing the systems that make the Internet work, Cisco is playing a major role in helping customers thrive in the explosive Internet economy. As a result, we are growing faster than all of our key competitors and have been the fastest growing and most profitable company in the history of the computer industry.
- John Chambers
It is possible to become world-class, enter the top 5% of performers in the world, in almost any subject within 6-12 months, or even 6-12 weeks.
- Timothy Ferriss
Faith is being sure of what we hope for and certain of what we do not see. HEBREWS 11:1.
- Joel Olsteen
If you can see the invisible, God will do the impossible.
- Joel Olsteen
Blind we are, if creation of this clone army we could not see.
- Yoda
Run your business in harmony with God’s laws.
- David Green
When men are fighting for their lives they are not often disposed to be complimentary to those who are trying to kill them.
- Winston Churchill
I will say that walking down the street, getting on the subway, taking the elevator, if there’s one or two people and they say, ‘Great job, Mayor,’ that is a real turn-on. I mean, anybody that wouldn’t find that satisfying, rewarding, exciting, thrilling – I think they should see the doctor.
- Michael Bloomberg
I believe that Ronald Reagan will someday make this country what it once was… an arctic wilderness.
- Steve Martin
Life isn’t fair. It’s true, and you still have to deal with it. Whining about it rarely levels the playing field, but learning to rise above it is the ultimate reward.
- Harvey Mackay
Barring serious accidents, if you are not preoccupied with worry and you work hard, you can look forward to a reasonably lengthy existence…. Its not the hard work that kills, its the worrying that kills.
- Thomas Edison
Winners expect to win, they expect victory, and they expect success!
- Zig Ziglar
One of the jobs of a manager is to instill confidence, pump confidence into your people. And when you’ve got somebody who’s raring to go and you can smell it and feel it, give ’em that shot.
- Jack Welch
If our company isn’t good enough to win, then do we need to exist at all?
- Ben Horowitz
The most amazing philanthropists are people who are actually making a significant sacrifice.
- Bill Gates
The thing that I’m going to focus on today is essentially the cloud that has been over Nike’s head over the last couple years.
- Phil Knight
History with its flickering lamp stumbles along the trail of the past, trying to reconstruct its scenes, to revive its echoes, and kindle with pale gleams the passion of former days. What is the worth of all this? The only guide to a man is his conscience; the only shield to his memory is the rectitude and sincerity of his actions. It is very imprudent to walk through life without this shield, because we are so often mocked by the failure of our hopes and the upsetting of our calculations; but with this shield, however the fates may play, we march always in the ranks of honor.
- Winston Churchill
In time, we lose our freshness and spontaneity of true conversation. These are areas in which everyone interested in self-improvement will seek to improve.
- Dale Carnegie
A half-billion-dollar subsidy was unthinkable in the mid-2000s. It’s unthinkable today. There was only one moment where that was possible, and Tesla played it perfectly.
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It begins by rejecting the unjust tyranny of Chance. You are not a lottery ticket.
- Peter Thiel
George W. Bush stated, I do not need to explain why I say things. That’s the interesting thing about being the president. Maybe somebody needs to explain to me why they say something, but I don’t feel like I owe anybody an explanation. That’s when I knew Bush was headed for trouble. With all due respect for the office, I completely disagree with him. In my view, it’s the leader’s responsibility to explain his or her actions every step of the way. And the higher up you are, the more important it is.
- David Novak
When you stop planning and preparing . . . you stop winning.
- Zig Ziglar
What kind of business world are we living in?
- Jack Ma
Will this business still be around a decade from now? Numbers alone won’t tell you the answer, instead you must think critically about the qualitative characteristics of your business.
- Peter Thiel
I had this very rich sense of how the metropolis was living and breathing.
- Jack Dorsey
I was so mad I ran a personal record.
- Phil Knight
You’d believe that a patient with hypertension, if you know you have hypertension or diabetes, you would take your drug every day. The compliance rate is more like 30% or 40%. Which means that 60% of patients don’t take their drugs, and they actually go into these crises, end up in the hospital.
- Patrick Soon-Shiong
But I know newspapers. They have the first amendment and they can tell any lie knowing it’s a lie and they’re protected if the person’s famous or it’s a company.
- Steve Wozniak
Rockets are cool. There’s no getting around that.
- Elon Musk
Throughout this quarter of a century, the entrepreneurial outlook, versatility and vision of our employees have remained the crucial elements of our success…
- Cheng Yu-tung
I have many children, as you seek you may find that this the last one till he must die before he must reach the becoming of mankind. Many men have failed but i have surpassed their expectation of being a Jedi master.
- Yoda
When two partners always agree, one of them is not necessary. If there is some point you haven’t thought about, be thankful if it is brought to your attention.
- Dale Carnegie
Nonviolence is a powerful and just weapon. which cuts without wounding and ennobles the man who wields it. It is a sword that heals.
- Martin Luther King Jr.
When it comes to Starbucks, I take every threat very personally.
- Howard Schultz
The new information technology… Internet and e-mail… have practically eliminated the physical costs of communications.
- Peter Drucker
Fact: If standard of living is your number one objective, quality of life almost never improves. But if quality of life is your number one objective, standard of living invariably improves.
- Zig Ziglar
Always remember that your present situation is not your final destination. The best is yet to come.
- Zig Ziglar
Control, control, you must learn control!
- Yoda
I’ve always been very happy. I’ve always been easy going and I’ve always been very encouraging, it’s just my personality.
- Joel Olsteen
The Effective Executive itself is not a book on what people at the top do or should do. It is addressed to everyone who, as a knowledge worker, is responsible for actions and decisions which are meant to contribute to the performance capacity of his organization
- Peter Drucker
By working only when you are most effective, life is both more productive and more enjoyable. It’s the perfect example of having your cake and eating it, too.
- Timothy Ferriss
Sometimes when you take strong stands, if you’re not called to do it, you’re dividing the audience you’re trying to reach.
- Joel Olsteen
Every day brings a chance for you to draw in a breath, kick off your shoes, and dance.
- Oprah Winfrey
If I do you a favor you will reciprocate even in greater measure if possible. Through the proper use of this law / can get you to do whatever I wish you to do. If I wish you to dislike me and to lend your influence toward damaging me, I can accomplish this result by inflicting upon you the sort of treatment that I want you to inflict upon me through retaliation.
- Napoleon Hill
In two or three minutes Mr. Roosevelt came through. “Mr. President, what’s this about Japan?” “It’s quite true,” he replied. “They have attacked us at Pearl Harbour. We are all in the same boat now.
- Winston Churchill
I think the acquisition of consumers might be on the verge of being mapped. The battlefield is going to be retention and lifetime value.
- Gary Vaynerchuk
The first is the result of a decision to act—to do something. This type of mistake is made with incomplete information, as it’s impossible to have all the facts beforehand. This is to be encouraged. Fortune favors the bold. The second is the result of a decision of sloth—to not do something—wherein we refuse to change a bad situation out of fear despite having all the facts. This is how learning experiences become terminal punishments, bad relationships become bad marriages, and poor job choices become lifelong prison sentences.
- Timothy Ferriss
The first real thought that I had of something that I might do was to write for car magazines, because I always had a car thing.
- Jerry Seinfeld
We are in the process of creating a group that has a broader business mix, better quality income streams and a stronger balance sheet. In doing so, our risk profile is spread out and we can better explore the growth potential across our five core businesses – property, hotels, infrastructure, services and telecommunications.
- Cheng Yu-tung
Los líderes son vulnerables, no controladores, y nos llevan a un lugar nuevo, no a la seguridad barata, rápida y sumisa.
- Seth Godin
There is little success where there is little laughter.
- Andrew Carnegie
believe God is going before my child lining up the right people to come across his path, taking away the wrong people, breaking every force of darkness, opening his eyes to every deception, and giving him the wisdom to make good choices to fulfill his destiny.” The Scripture tells us that the people of Israel.
- Joel Olsteen
I’m a big fan of all-you-can-eat plans, because they’re simpler for customers.
- Jeff Bezos
The perfect target market for a startup is a small group of particular people concentrated together and served by few or no competitors. Any big market is a bad choice, and a big market already served by competing companies is even worse. This is why it’s always a red flag when entrepreneurs talk about getting 1% of a $100 billion market. In practice, a large market will either lack a good starting point or it will be open to competition, so it’s hard to ever reach that 1%. And even if you do succeed in gaining a small foothold, you’ll have to be satisfied with keeping the lights on: cutthroat competition means your profits will be zero.
- Peter Thiel
You may never get to that perfect world that you’re waiting for where everything’s going to be perfect and you got that much money and your house paid off.
- Joel Olsteen
I’ve done a number of Super Bowl ads. And that is the best advertising of the year. That is when people realize they’re going to be compared directly against other ads.
- Jerry Seinfeld
When I was 17 or 18 I wanted to become a wine expert, and my parents wouldn’t let me drink. So I was devastated. All I could do was read, and I read and I read. And I’d read something like, you know, ‘Subtle hints of cassis.’
- Gary Vaynerchuk
No one has done a study on this, as far as I can tell, but I think Facebook might be the first place where a large number of people have come out. We didn’t create that – society was generally ready for that. I think this is just part of the general trend that we talked about, about society being more open, and I think that’s good.
- Mark Zuckerberg
That Newport store was really the beginning of where Walmart is today. We did everything. We would wash windows, sweep floors, trim windows. We did all the stockroom work, checked the freight in. Everything it took to run a store. We had to keep expenses to a minimum. That is where it started, years ago. Our money was made by controlling expenses. That, and Sam always being so ingenius. He never stopped trying to do something different. One thing, though: I never forgave him for was making me clean out that damned ice cream machine.
- Bud Walton
This defines entrepreneur and entrepreneurship – the entrepreneur always searches for change, responds to it, and exploits it as an opportunity.
- Peter Drucker
Creating a sense of urgency around change initiatives is especially hard to do. Human nature seems to be hardwired to adhor change, and people will do everything in their power to resist it. I once heard this explained to another Pepsi consultant. His philosophy was that in order to drive change, you need to create what he called, the burning platform. This burning-platform image was an oil rig in the North Sea that has caught fire and the only way to save yourself is to jump into the frigid water and swim to the lifeboat. You know the jump might kill you, but you jump anyway, not because you think it might be a good idea, but because you had no choice. That’s creating a sense of urgency.
- David Novak
If salespeople don’t probe well for background information, they don’t know how to launch the presentation.
- Jerry Vass
By far the most difficult skill I learned as a C.E.O. was the ability to manage my own psychology. Organizational design, process design, metrics, hiring and firing were all relatively straightforward skills to master compared with keeping my mind in check.
- Ben Horowitz
I don’t generally read a lot of fiction.
- Bill Gates
The final test of a leader is that he leaves behind him in other men the conviction and the will to carry on.
- Walter Lippmann
Being the first mover doesn’t do you any good if someone else comes along and unseats you. It’s much better to be the last mover—that is, to make the last great development in a specific market and enjoy years or even decades of monopoly profits.
- Peter Thiel
I am what I am and, you know, I’m a very lucky guy.
- Michael Bloomberg
Speed is of the essence in responding to a crisis situation, and our focus is squarely on mobilizing resources to help in the relief and rebuilding efforts, while also helping customers and employees recover.
- John Chambers
I don’t like typing messages on my phone. Some people get used to it.
- Bill Gates
What makes a startup employee instantly distinguishable to outsiders is the branded T-shirt or hoodie that makes him look the same as his co-workers. The startup uniform encapsulates a simple but essential principle: everyone at your company should be different in the same way—a tribe of like-minded people fiercely devoted to the company’s mission.
- Peter Thiel
We were comfortable with first-quarter results.
- John Chambers
K to 12 is partly about babysitting the kids so the parents can do other things.
- Bill Gates
Think of the transformation as a process of buildup followed by breakthrough, broken into three broad stages: disciplined people, disciplined thought, and disciplined action. Within each of these three stages, there are two key concepts, shown in the framework and described below. Wrapping around this entire framework is a concept we came to call the flywheel, which captures the gestalt of the entire process of going from good to great.
- James C. Collins
Companies, exist and evolve over time and in fact they have multiple founding moments.
- Jack Dorsey
By my count, more business leaders have failed and derailed because of arrogance than any other character flaw.
- Harvey Mackay
In the game of life, money is just how we keep score.
- Clay Clark
The future of gambling is as an entertainment business.
- Lui Che Woo
Always will I take another step. If that is of no avail I will take another, and yet another. In truth, one step at a time is not too difficult.
- Og Mandino
You cannot consistently perform in a manner which is inconsistent with the way you see yourself.
- Zig Ziglar
I have plenty of money to do what I want to do, and I have the relationships.
- Timothy Ferriss
Twenty years and $40 billion. They seem like good round numbers.
- Michael Dell
It does matter what you do. You should focus relentlessly on something you’re good at doing, but before that you must think hard about whether it will be valuable in the future.
- Peter Thiel
We see our customers as invited guests to a party, and we are the hosts. It’s our job every day to make every important aspect of the customer experience a little bit better.
- Jeff Bezos





